respiratory system diseases : asthma
What is fluticasone?
Fluticasone is a synthetic
glucocorticoid that prevents the release of substances that cause inflammation
in the body, such as histamine and leukotrienes, and acts as a vasoconstrictor
and anti-inflammatory. It reduces inflammation of bronchial cells, so it is
used to treat bronchial cell inflammation, in maintenance and control treatment
of persistent asthma.
This medicine is used by asthma
patients every day, even if the patient feels better. Do not reduce the dose or
stop fluticasone orange inhaler unless your doctor tells you to do so.
Fluticasone side effects
The medicine may cause some side
effects, such as:
Diarrhea.
epistaxis.
Upper respiratory tract infection.
Muscle pain.
Hoarseness.
cough.
Back Pains.
pharyngitis.
Fever.
Abdominal pain.
Loss of sense of taste.
Candidiasis.
Itchy throat.
headache.
Upper respiratory tract infection
epistaxis
Muscle pain
Hoarseness
cough
Back pain
Tummy ache
Loss of taste
Oral candidiasis
Itchy throat
headache
Loss of sexual desire
Menstrual problems
pharyngitis
fever
Diarrhea
What are the uses of fluticasone?
Fluticasone
is used in the following cases:
Continuous treatment in the case of
chronic asthma, and is also used in the case of acute asthma.
Salmeterol is added to fluticasone,
to be used in the maintenance treatment of asthma that is not completely
controlled with inhaled corticosteroids, or if the condition stabilizes with
salmeterol and fluticasone.
Treatment of seasonal and annual
allergic diseases.
Treating sinus infections.
Chronic obstructive pulmonary
disease.
What are the contraindications for using fluticasone?
It is prohibited to use fluticasone
orange asthma spray without consulting a specialist doctor in the following
cases:
Hypersensitivity to fluticasone or
any of the components of the drug.
What are the precautions for using fluticasone?
Fluticasone should be used with
caution under the supervision of a doctor in the following cases:
Pregnancy and breastfeeding period,
as there are not sufficient studies on the safety of its use by inhalation, and
it should be used with caution.
Use with caution in cases of
thyroid dysfunction.
Kidney failure.
Liver failure.
Heart disease.
diabetes.
Glaucoma.
Osteoporosis.
What are the drug interactions of fluticasone?
It is preferable to have a doctor
or pharmacist check all medications, herbs, vitamins and nutritional
supplements before starting treatment.
Including taking fluticasone
asthma spray in conjunction with the following medications:
Adrenal gland insufficiency.
Mental illnesses, such as
depression.
There is a risk of epilepsy.
Gastrointestinal diseases, such as
ulcers.
Delayed wound healing. The use of
nasal corticosteroids should be avoided in patients who suffer from a nasal
ulcer, nasal surgery, or nasal injury until healing occurs.
Children: Orange asthma inhaler for
children should be used under the supervision of a doctor, as cortisone delays
and prevents children’s growth.
Fluticasone should be discontinued gradually, not suddenly.
Other types of corticosteroids.
Fluoroquinone.
Antifungal medications, such as
ketoconazole.
HIV medications, such as ritonavir.
What are the doses of fluticasone and how to use it?
Dosages for using fluticasone in
cases of persistent asthma:
Adults: 100-250 mcg twice a day; Up
to 1000 micrograms twice a day is used in severe asthma, and requires
specialist supervision for patients who require more than 500 micrograms as a
daily dose.
Children older than 4 years: 50-100
mcg twice a day; Up to 200 micrograms twice a day in severe persistent asthma
that requires specialist supervision for children <5 years, which requires
> 250 micrograms as a daily dose.
Fluticasone can also be given via a nebulizer in severe chronic asthma:
The usual adult dose is: 0.5 to 2
mg twice daily.
Children aged 4-16 years can be
given 1 mg twice daily.
What are the pharmaceutical forms of fluticasone?
Fluticasone orange asthma spray
is available in the following dosage forms:
Powder inside rotary tablet device
for oral inhalation: 50 mcg/inhalation, 100 mcg/inhalation, 250 mcg/inhalation,
500 mcg/inhalation.
Powder inside the nebulizer for
oral inhalation in the form of propionate: 44 micrograms/inhalation, 125
micrograms/inhalation, and 220 micrograms/inhalation.
Suspension in nasal spray: 50
mcg/inhalation.
What are the storage conditions for fluticasone?
Fluticasone should be stored away
from light and moisture, at a room temperature below 25 degrees Celsius, and
kept out of the reach of children.
How to use fluticasone?
Provide the following advice and
information to the patient before using fluticasone orange asthma inhaler:
Fluticasone is sometimes added to
salmeterol.
A dispenser is used with the
inhaler to administer the specified dose.
This medication is not used for
immediate relief of severe asthma symptoms.
It is recommended to rinse your
mouth after using this medicine, spit out the water and avoid swallowing it.
Use this medication every day even
if you feel better. The dose is not reduced or stopped unless the doctor
advises doing so.
The dose is reduced every 3 months
by approximately 25% if asthma is controlled.